Intranasal vaccination

Intranasal Vaccination with Proinsulin DNA

Effect of PRRS vaccination on average daily gain: A comparison of intranasal and intranasal-intramuscular administration

SAS: Iowa Select Farms, Iowa Falls, Iowa 50126, e-mail: [email protected]; JJZ: Iowa State University; DDP, MBR: NOBL Laboratories orcine reproductive and respiratory syndrome (PRRS) causes production and financial losses in swine herds worldwide.1–3 Several researchers have reported that PRRS virus (PRRSV) infection may have an adverse effect on nursery performance.4,5 Kerkaert, et al.,...

Intranasal vaccination of mice against infection with Mycobacterium tuberculosis.

The intranasal (i.n.) route of immunisation, has recently been of active interest in endeavours to improve the efficacy of vaccination against a number of respiratory infections. Here, we examined the outcome of tuberculous infection in BALB/c mice. I.n. application of the BCG-Pasteur strain was found to be highly protective against challenge infection with the pathogenic H37Rv strain given aft...

Respiratory PCR detects influenza after intranasal live-attenuated influenza vaccination

From 2013 an annual nasal live-attenuated influenza vaccine (LAIV—Fluenz) is available for all children in the UK aged 2 and 3 years and other ‘at-risk’ children, as part of the National Health Service (NHS) childhood vaccination programme. 2 The vaccine contains reassortant influenza viruses; two influenza A viruses (H1N1 and H3N2) and one influenza B virus, and has previously been used in chi...

Intranasal Vaccination Promotes Detrimental Th17-Mediated Immunity against Influenza Infection

Influenza disease is a global health issue that causes significant morbidity and mortality through seasonal epidemics. Currently, inactivated influenza virus vaccines given intramuscularly or live attenuated influenza virus vaccines administered intranasally are the only approved options for vaccination against influenza virus in humans. We evaluated the efficacy of a synthetic toll-like recept...